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human liver cytosol fraction (hlc) (Sekisui XenoTech)

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Sekisui XenoTech human liver cytosol fraction (hlc)
Human Liver Cytosol Fraction (Hlc), supplied by Sekisui XenoTech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/human+liver+cytosol/human+liver+cytosol/pmc10835938__40246_2024_579_MOESM1_ESM-0-6-20
Average 90 stars, based on 1 article reviews

human liver cytosol fraction (hlc) - by Bioz Stars, 2026-10

90/100 stars

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Control:

Article Title: The Impact of Age and Genetics on Naltrexone Biotransformation.
Article Snippet: .. Pooled human liver cytosol (n 5 200, mixed gender, lot #1410229) was purchased from Xenotech (Kansas City, KS) and was used as an internal assay control (minimal interday variability %CV 5 5.5). ..

Incubation:

Article Title: Novel progestogenic androgens for male contraception: design, synthesis, and activity of C7 α-substituted testosterone†.
Article Snippet: Aliquots were removed at 0, 15, 30, and 60 min, mixed with acetonitrile containing 1000 ng/ml d3-T (Sigma-Aldrich); vortexed; centrifuged; and diluted with 0.1% formic acid in water for analysis by LC–MS/MS (see below LC–MS/MS Analysis). .. For 5α-reductase analysis, test articles (1 μM) were incubated at 37◦C with 0.5 mg/ml human liver cytosol (Xenotech, Kansas City, KS), 3.3 mM MgCl2, and 2.5 mM NADPH in 0.1 M phosphate buffer, pH 7.4, with and without 50 μM finasteride, a 5α-reductase type 2 specific inhibitor (SigmaAldrich). .. Aliquots were removed at 0, 15, 30, 60, 90, and 120 min; mixed with acetonitrile containing 100 ng/ml d3T (Sigma-Aldrich); vortexed; centrifuged; and diluted with 0.1% formic acid in water for analysis by LC–MS/MS (see below LC–MS/MS Analysis).

other:

Article Title: Metopimazine is primarily metabolized by a liver amidase in humans
Article Snippet: Pooled human liver S9 (50‐donor mixed gender) and human intestine S9 (10‐donor mixed gender) fractions and pooled human liver cytosol (HLC, 50‐donor mixed gender) were purchased from Xenotech.

Article Title: 6-oxo-pipecolic acid quantitation by mass spectrometry
Article Snippet: D3-a-Aminoadipic acid (d3-DL-α-AAA) was acquired from CDN Isotopes (Quebec, Canada), and all other reagents were procured from Fisher Scientific (Pittsburgh, PA).